Welcome to the Dietz Lab at TU Munich.
Towards synthetic nanomachines.
Towards precise nanoengineering.
Towards efficient assembly.
Sequence, shape, and function. Synthetic Biology by DNA.
Inspired by the rich functionalities of natural macromolecular assemblies such as enzymes, molecular motors, and viruses, we seek means for building artifical nanodevices that can execute user-defined tasks. Molecular self-assembly with DNA* is an attractive route to achieve this goal and allows for building nanodevices that open new paths to scientific discovery in biomolecular physics and protein science**.
(*) A primer to DNA origami.;
(**) More about our research goals.
Selected Publications
- XC Bai, TG Martin, SJ Scheres, H Dietz: 'Cryo EM structure of a 3D DNA origami object' PNAS 2012
- JP Sobczak, TG Martin, T Gerling, and H Dietz: 'Rapid folding of DNA into nanoscale shapes at constant temperature' SCIENCE 2012
- M Langecker, V Arnaut, TG Martin, J List, S Renner, M Mayer, H Dietz, and F Simmel: 'Synthetic lipid membrane channels formed by designed DNA nanostructures' SCIENCE 2012
- H Dietz, SM Douglas, and WM Shih: 'Folding DNA into twisted and curved nanoscale shapes.' SCIENCE 2009
- SM Douglas, H Dietz, T Liedl, B Hogberg, F Graf, and WM Shih:
'Self-assembly of DNA into nanoscale three-dimensional shapes.' NATURE 2009
Our Research:
- Current Directions
- Published Results
- On Biomolecular Nanotechnology
- Nanotechnology and the Double Helix
- Resources and Links
Our Partners:
- Scheres Lab,
LMB Cambridge - Bathe Lab,
MIT Boston - Carter Lab,
LMB Cambridge - Rief Lab, TU Munich
- Simmel Lab, TU Munich
Our Sponsors
We are thankful for financial support from the Deutsche Forschungsgemeinschaft via the CIPSM, NIM, and SFB863 programs. Further support comes from the European Research Council, the TUM IAS, and the Fonds der Chemischen Industrie.
© Laboratory for Biomolecular Nanotechnology at the Technische Universität München.